The rate at which patients respond to TRT varies, depending on individual factors such as underlying health conditions, medications, body fat percentage, and the degree of testosterone deficiency. Some may notice improvements as early as the first injection, while for others, it may take two to three months to experience significant changes. Most patients begin to feel better within about four weeks, though initial progress is often subtle and builds gradually over time. If there is little to no improvement after several weeks, we’ll run additional lab tests and consider alternative treatment approaches to ensure the best outcome.

There is no age limit for testosterone replacement therapy; it produces benefits for men of all ages.

Increase in Red Blood Cells
Testosterone therapy may increase red blood cell production, which can be beneficial for those with anemia. However, we carefully monitor this. If necessary, a simple procedure called therapeutic phlebotomy (blood donation) will be performed to reduce red blood cell levels. It's important to note that while polycythemia refers to any rise in red blood cells, erythrocytosis specifically denotes an increase in red cell mass. TRT can elevate hemoglobin and hematocrit levels with or without impacting red cell mass.

Prostate Effects
If you have a history of prostate cancer, clearance from your urologist is required before starting TRT. It’s important to understand that testosterone does not cause prostate cancer.

Skin Reactions
Some patients may experience acne or oily skin, though these side effects are uncommon and typically temporary if they do occur. Some patients experience minor side effects and temporary inflammation due to injections. 

Sperm Count
Testosterone therapy can reduce sperm production during treatment, but it is not considered a contraceptive, as men can still conceive while on testosterone.

Fluid Retention
While rare, those with a history of heart failure or kidney disease should be cautious, as TRT may cause fluid retention.

For many men, hypogonadism is a long-term condition. While some may experience temporary drops in testosterone due to factors like a severe infection or short-term physical or emotional stress, most men who have been dealing with Low-T symptoms for more than several months often face a chronic condition that requires ongoing testosterone replacement. Just as a diabetic may need insulin or someone with hypothyroidism may require thyroid medication to stay healthy, men with hypogonadism often need ongoing testosterone replacement therapy to maintain their best health and well-being over the long term.